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Bristol Myers Squibb
Princeton, NJ, United States
21 days ago
Matterworks
Cambridge, MA, United States
24 days ago
Waters
Newark, DE, United States
27 days ago
Omeros
Seattle, WA, United States
30+ days ago
Bristol Myers Squibb
Princeton, New Jersey, United States
21 days ago

Description

The Department of Clinical Biomarker Immunoassay & Mass Spectrometry (CBIMS) in Translational Medicine at Bristol-Myers Squibb in Princeton, NJ is seeking a contract personnel (Research Scientist level) to provide expertise and laboratory support for the quantitative analysis of biomarkers in drug discovery and development.

The major responsibility for this position is to develop and execute LC-MS based methods in support of biomarker (small molecules, peptides and proteins, etc) analysis, including assay development, validation, troubleshooting and sample analysis for non-clinical and clinical studies from different therapeutic areas. The selected candidate will also report study sample results to clients following the department policies and procedures, and communicate laboratory results and findings in cross-disciplinary project team and department meetings. The selected candidate must be highly motivated, organized, with excellent communication skills (oral and written), detail oriented, and most importantly a good team player.



Requirements

  • MS or PhD in analytical chemistry, proteomics, protein chemistry or related disciplines with experience (3-5 years for MS, 1-3 years for PhD) in the areas of targeted quantitative proteomics or LC-MS quantitative analysis in biological matrices is required. Additional background in immunology or biology is a plus.
  • Good knowledge of LC-MS instrumentation for small and large molecule quantitation; experienced in both triple quadrupole MS and high resolution mass spectrometry (HRMS) platforms.
  • Hands on experience on Thermo’s Q Exactive, Sciex’s Triple TOF 6600+ or Bruker’s TimsTOF Pro platforms is desirable.
  • Experience of immuno-capture LC-MS assay workflow, including immuno-capture with bead or cartridge formats, enzymatic digestion, and basic knowledge of ligand-binding assay (LBA) is a plus.
  • Capability of performing complex and multiplex biomarker LC-MS assay development in biological matrices.
  • Familiar with Skyline, Spectronaut™ and other advanced protein analysis software for targeted proteomics is desirable.
  • Knowledge and hands on experience in proteomics is a plus.
  • Ability to keep accurate and timely documentation per departmental guidelines, timely document and communicate abnormal laboratory observations.
  • Possess excellent communication and organizational skills in a cross-functional environment.

Job Information

  • Job ID: 59622640
  • Location:
    Princeton, New Jersey, United States
  • Position Title: Research Scientist -LC-MS, Biomarker
  • Company Name: Bristol Myers Squibb
  • Industry: Bio-analysis,HPLC,LC-MS,Quantitation
  • Job Function: Res. & Dev. Scientist
  • Job Type: Contract
  • Job Duration: 1-2 Years
  • Min Education: 1
  • Min Experience: 5-7 Years
  • Required Travel: 0-10%
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